Management of acute poisoning with non steroidal anti-inflammatory agents consists essentially supportive and symptomatic measures. There is no typical picture resulting from an overdosage of diclofenac.
The therapeutic measures to be taken in case of overdosage are as follows: supportive and symptomatic treatment should be given for complications, such as hypotension, renal failure, convulsions, gastrointestinal irritation and respiratory depression.
Special therapies, such as forced diuresis, dialysis or haemoperfusion are probably of no help in eliminating non steroidal anti-inflammatory agents, because of their high protein binding rate and extensive metabolism.